Resistance training reduces pain in women with fibromyalgia / O treinamento resistido reduz a dor em mulheres com fibromialgia

Resistance training (RT) is an intervention strategy for the treatment of fibromyalgia (FM) that has low cost, easy access, easy application and a positive effect on general health maintenance. Objective:To investigate the effect of four weeks of RT on pain in patients with FM. Method:This is a non-randomized controlled clinical trial with fifty-four women with FM (age: 53.74 ± 8.54 years). Patients were allocated to the intervention group (n= 33) and the control group (n= 21). The intervention consisted of a four-week supervised RT program. For pain assessment, an algometer and a visual analogue scale were used. To assess differences after the intervention, ANOVA two-way was used. Results:Patients in the intervention group had a significant reduction in pain perception and increased pain threshold, but there was no difference when compared to the control group. Conclusions:The practice of RT for four weeks reduces the pain of patients with FM; however, no significant differences were found with the control group. For this reason, the significant results of this study should be considered with caution, reinforcing the need for further studies.

O treinamento resistido (TR) é uma estratégia de intervenção para o tratamento da fibromialgia (FM) que possui baixo custo, fácil acesso, fácil aplicação e efeito positivo na manutenção geral da saúde. Objetivo: Investigar o efeito de quatro semanas de TR na dor de pacientes com FM. Método: Trata-se de um ensaio clínico controlado não randomizado com cinquenta e quatro mulheres com FM (idade: 53,74 ± 8,54 anos). As pacientes foram alocadas no grupo intervenção (n= 33) e no grupo controle (n= 21). A intervenção consistiu em quatro semanas de um programa de TR supervisionado. Para a avaliação da dor foi utilizado um algômetro e a escala visual analógica. Para avaliar as diferenças após a intervenção, foi utilizada a ANOVA de dois fatores. Resultados: Os pacientes do grupo intervenção tiveram redução significativa da percepção da dor e aumento do limiar de dor, mas não houve diferença quando comparados ao grupo controle. Conclusão: A prática do TR por quatro semanas reduz a dor de pacientes com FM, entretanto, não foram encontradas diferenças significativas com o grupo controle. Por esse motivo, os resultados significativos deste estudo devem ser considerados com cautela, reforçando a necessidade de novos estudos.

Fatal hepatitis B reactivation treated with entecavir in an isolated anti-HBs positive lymphoma patient: a case report and literature review

Hepatitis B virus [HBV] reactivation is a well-recognized complication that occurs in lymphoma patients who undergo chemotherapy. Only very few cases of HBV reactivation in patients with isolated antibody against hepatitis B surface antigen [anti-HBs] have been reported. We present a case of a 78-year-old woman diagnosed with diffuse large B cell non-Hodgkin's lymphoma who only displayed a positive anti-HBs, as the single possible marker of occult HBV infection, before starting therapy. She was treated with several chemotherapeutic regimens [including rituximab] for disease relapses during 3 years. Forty days after the last cycle of chemotherapy, she presented with jaundice, markedly elevated serum aminotransferase levels, and coagulopathy. HBV serology showed positivity for HBsAg, anti-HBc and anti-HBs. HBV DNA was positive. Antiviral treatment with entecavir was promptly initiated, but the patient died from liver failure. A review of the literature of HBV reactivation in patients with detectable anti-HBs levels is discussed